| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0e94ccdf15d7a200da9f39f72d40ae5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B21-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B67-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-20 |
| filingDate |
1998-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b33749ce9f2d15df14c396952f46fa |
| publicationDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H11209357-A |
| titleOfInvention |
In vivo staining composition for confirming dysplastic tissue, method for producing and using the same |
| abstract |
(57) [Problem] To provide a dyeing composition having a high ratio of toluidine blue O and stable quality, and a method for producing the same. The present invention provides a method for confirming a malformed tissue using the staining composition and a method for analyzing the staining composition. SOLUTION: N, N-dimethyl-p-phenylenediamine is oxidized to produce 2-amino-5-dimethylaminophenylthiosulfonic acid, which is then oxidized and condensed with o-toluidine to form indaminethiosulfone. Generating an acid and further oxidizing to close the indamine ring to produce a toluidine blue O (TBO) -containing reaction product, wherein the complexation occurs prior to formation of the TBO-containing reaction product. It is characterized by introducing a reagent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003139752-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005535605-A |
| priorityDate |
1997-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |