| abstract |
(57) [Summary] Piper Metishikum (Piper Met) (Hysticum) or an extract thereof as an active ingredient, and can be used as a skin external preparation or an oral administration preparation. [Effect] It has excellent testosterone-5α-reductase inhibitory activity and can be suitably used as an external preparation for skin, an oral administration agent, etc., alopecia, acne (acne vulgaris), benign prostatic hyperplasia, prostate It is useful for prevention and treatment of cancer and the like. |