| abstract |
[PROBLEMS] To provide a HOFNH30 polypeptide and polynucleotide and a method for producing the polypeptide by a recombinant method. SOLUTION: The nucleotide sequence encoding the HOFNH30 polypeptide of SEQ ID NO: 2 has at least 8 An isolated polynucleotide comprising a nucleotide sequence that encodes a polypeptide that is 0% identical and has the activity of a HOFNH30 polypeptide, or a nucleotide sequence that is complementary to this nucleotide sequence. [Effect] HOFNH30 polypeptide and polynucleotide are used for infectious disease, pain, cancer, diabetes, obesity, anorexia nervosa, bulimia, asthma, Parkinson's disease, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, narrowing Heart disease, myocardial infarction, ulcer, It is useful for treating conditions such as allergy, benign prostatic hypertrophy, mental and neurological disorders, and for diagnosing such conditions. |