| abstract |
(57) [Problem] To provide a liposome preparation containing 1- (2-C-cyano-2-deoxy-β-D-arabino-pentofuranosyl) cytosine which is an antitumor agent. I do. SOLUTION: Cholesterol is contained as an essential component as a lipid constituting a liposome, and di (C 10-18 alkanoyl or alkenoyl) phosphatidylcholine, di (C 10-18 alkanoyl or alkenoyl) phosphatidylglycerol and / or Or the polyethylene glycol moiety has an average molecular weight of 1,000 to 5 A liposome formulation containing 000 N-monomethoxy polyethylene glycol succinyl-di (C 10-18 alkanoyl or alkenoyl) phosphatidylethanolamine. |