abstract |
(57) [Problem] To provide an antibody against a glycoprotein ligand having specific binding to GMP-140. An antibody against a glycoprotein ligand having specific binding to GMP-140. The glycoprotein ligand comprises a fucosylated sialylated glycoproteins containing sialyl Le x portion, and having a relative molecular weight of about 120,000 apparent by evaluation by SDS-PAGE under reducing conditions. This antibody is effective to specifically block GMP-140 binding to a glycoprotein ligand for GMP-140. |