abstract |
(57) [Problem] To provide a novel camptothecin derivative which is water-soluble and has excellent antitumor activity. SOLUTION: The novel camptothecin derivative has a general formula (1): (Wherein, R 1 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R 2 is an alkyl group having 0 to 4 carbon atoms having 1 to 6 carbon atoms, A camptothecin derivative represented by a halogen atom, an alkoxy group, a hydroxyl group, and R 3 is a lower alkylamino group, a di-lower alkylamino group, an arylamino group, a cyclic amino group or a lower alkoxy group) and salts thereof. |