| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b1c7560aa50b0da1769cd5b6f735b69 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D505-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D505-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D503-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 |
| filingDate |
1997-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ea92548407df740745ae0a7e7256653 |
| publicationDate |
1999-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H1112276-A |
| titleOfInvention |
Method for producing β-lactam derivative |
| abstract |
PROBLEM TO BE SOLVED: To remove a carboxylic acid protecting group X of a β-lactam derivative having a protected carboxyl group represented by the general formula (1) as a reusable alcohol and to remove the carboxyl group from the above general formula (2) The present invention provides a technique for efficiently producing a carboxylic acid of a β-lactam derivative without using an expensive reagent. SOLUTION: General formula (1) A-COO-X (1) (wherein A represents a β-lactam derivative residue. X is a benzyl group or a phenyl group having an electron-donating group as a substituent on a phenyl ring) A diphenylmethyl group which may have an electron-donating group on the ring.) The carboxyl group-protected β-lactam derivative is treated with aluminum halide in an ether solvent to obtain a compound represented by the general formula (2): A-COOH (2) (wherein A is as defined above), a process for producing a β-lactam derivative, wherein the leaving group X can be recovered and reused as X-OH. . |
| priorityDate |
1997-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |