| abstract |
(57) [Summary] (Modified) [Problem] To provide a novel cysteine protease. A novel cysteine protease or a partial peptide thereof, a DNA encoding the protein, the D Recombinant vector containing NA, transformant, method for producing the protein, drug containing the protein or DNA, antibody to the protein, method for screening for compound that promotes or inhibits protease activity of the protein, for screening Compounds or salts thereof obtained by kits and screening. [Effect] The protein or the DNA encoding it is For example, agents for treating and preventing various diseases such as diabetic nephropathy, renal diseases such as glomerulonephritis, liver diseases such as liver fibrosis, pulmonary fibrosis, intervertebral disc herniation, spinal cord slip disease, sciatica, and marble disease. Can be used as a medicine. |