| abstract |
[PROBLEMS] To provide a novel arylacrylamide derivative which is effective as a selective agonist and antagonist of serotonin 1 (5-HT 1 ) receptor. SOLUTION: The following formula: A compound represented by the formula: As a specific example, 3- [2 -(4-methylpiperazin-1-yl) phenyl]- It becomes 2, N-diphenyl-acrylamide. The above compounds are effective psychotherapeutic agents, significant serotonin (5-HT 1) agonists and antagonists. |