abstract |
(57) [Summary] [PROBLEMS] To extract and isolate a novel medicinal component from Ginseng, which is used as a herbal medicine for various bleeding symptoms, liver diseases, etc. SOLUTION: Ginseng is extracted with hot methanol, the extract is liquid-liquid partitioned with ethyl acetate and water, n-butanol is added to the water transfer portion, liquid-liquid partitioned, and the butanol phase is separated. Phase silica gel column chromatography, The fraction was divided into five fractions, and the fourth fraction was subjected to reverse phase column chromatography. Three new saponin glycosides of the following formula were isolated from the methanol eluate. Embedded image |