http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H1077262-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33dafb5bbc2ec47ebcb7becbbe60f704 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02 |
| filingDate | 1996-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ea705f0808e26b7657c9a73604b46d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6315a5481dd183ce1ec425c519313a9b |
| publicationDate | 1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H1077262-A |
| titleOfInvention | Method for producing 11-cis-type retinal and synthetic intermediate useful for the method |
| abstract | PROBLEM TO BE SOLVED: To provide a method capable of producing 11-cis-type retinal with high yield and high selectivity using easily available raw materials, and to provide a synthetic intermediate therefor. SOLUTION: The following reaction formula; (Wherein R 1 is an alkyl group having 1 to 4 carbon atoms), and the formula (CH 3 ) 3 SiC — HCO 2 R 1 is added to the iron carbonyl complex aldehyde (1). Acting on an ester salt represented by Li + to form its ester (3) To produce ketone (4) by the action of Ph 3 SnCH 2 - Li + And reacting it with an alkali metal dialkylcyanomethylphosphonate salt to produce a nitrile (6), and then reacting with cupric halide to produce an 11-cis retinonitrile (7), which is reduced. And expressed by equation (8) 11 -Iron carbonyl complex produced by the method of the present invention for producing cis-type retinal and in the above step (synthetic intermediate) The above object is achieved by using (3), (4) or (6). |
| priorityDate | 1996-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.