| abstract |
PROBLEM TO BE SOLVED: To provide a hyperproliferative skin disease such as psoriasis and a neoplastic disease such as leukemia, and to inhibit skin hyperproliferation and tumor cells, and acne and seborrheic dermatitis. A compound useful for treating sebaceous gland disease or a pharmaceutical composition containing the same is provided. SOLUTION: The following formula (I): Wherein R is hydroxy and R ′ and R ″ are At the same time H, or together ＝ CH 2 , or R is hydrogen or fluoro, and R ′ and R ″ are Together with = CH 2 ), or a pharmaceutical composition containing this compound. |