| abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide a drug and a method effective for prevention or treatment of Helicobacter pylori infection. The compound of the following formula I: Or a pharmaceutically acceptable salt or hydrate thereof. Wherein R 1 is hydrogen or an optionally substituted phenyl, R 2 Is alkyl, phenyl, etc., R 3 is alkyl, phenyl or benzyl, R 4 to R 7 are hydrogen, alkyl, alkoxy, etc., X, Y and Z each independently represent carbon or nitrogen. It is an inhibitor of H. pylori and is therefore useful for treating and preventing peptic ulcers, gastritis, dyspepsia and gastric cancer. |