abstract |
(57) Abstract The present invention provides a 7-acyl-3-substituted carbamoyloxycephem compound which is an antifungal agent, a method for producing the same, and an antibacterial agent and intermediate comprising the compound. SOLUTION: General formula (1): (Wherein, A represents -CH = or -N =, R 1 represents a hydroxyl group, a lower alkoxy group, a fluorine-substituted lower alkoxy group or a protected hydroxyl group. R 2 and R 3 may be the same or different and are lower Represents an alkyl group or a substituted lower alkyl group, R 2 represents a hydrogen atom and R 3 represents a lower alkyl group which may be substituted, or a compound represented by the formula: Are saturated 4 to 6 containing one nitrogen atom. Represents a membered heterocyclic group or a morpholino group, which may be substituted. R 4 represents a carboxyl group or a protected carboxyl group. ) Or a pharmaceutically acceptable salt thereof, a method for producing the same, an antibacterial agent and an intermediate. |