| abstract |
(57) [Summary] [Object] To provide a novel cyclic amine derivative effective for treatment and prevention of diseases of the central nervous system, a method for producing the same, and a medicament containing the same as an active ingredient. A cyclic amine derivative represented by the following general formula or a pharmacologically acceptable salt thereof. Embedded image (In the formula, J is a lower alkyl group, a cyclohexyl group, a phenyl group, a pyridyl group, a pyrazyl group, a quinolyl group, a quinoxalyl group, a furyl group, and B is-(CH 2 ) n- , -NR 2- (CH 2 ) n- (R 2 is H, lower alkyl group, etc.), -CONR 3- (CH 2 ) n- (R 3 is H, lower alkyl group, etc.), - NH-CO- (CH 2) n -, -CH 2 -CO-NH -(CH 2 ) n -etc. (n is 0 to 10), T is N or C, K is an arylalkyl group, a cinnamyl group, a lower alkyl group, etc., q is 1 Means an integer of ] |