Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
filingDate |
1997-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aa315854eadf6e823ca7c023cb11472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8716c7bcd72e269bc7724df33d553324 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f9ccb2487ffd875d3df86b524876799 |
publicationDate |
1998-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H1066592-A |
titleOfInvention |
Method for producing lipstatin and tetrahydrolipstatin |
abstract |
PROBLEM TO BE SOLVED: To provide an improved method for producing lipstatin by fermentation by using a fed-batch culture method. SOLUTION: a) aerobically cultivating actinomycetes producing lipstatin in an aqueous medium free of fat and oil, and b) linoleic acid stabilized by an antioxidant, optionally A process for the production of lipstatin by fermentation, comprising the step of adding together with caprylic acid and N-formyl-L-leucine or preferably L-leucine to the broth. In addition, lipstatin can be isolated from the broth and hydrogenated to tetrahydrolipstatin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011515100-A |
priorityDate |
1996-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |