| abstract |
PROBLEM TO BE SOLVED: To provide 3-oxocarboxylic acid esters useful as humidifier ceramides, biodegradable polymers or synthetic intermediates for pharmaceuticals, etc., with high purity, high efficiency and complicated process. A novel manufacturing method that can be manufactured in a non-existent manner. SOLUTION: An acetoacetate is reacted with a calcium compound, a barium compound or a strontium compound in the presence of an organic solvent at a temperature of 10 to 120 ° C., further reacted with a carboxylic acid chloride, and acylated. By adding 1 to 5 times the molar amount of alcohol based on the compound, barium compound or strontium compound and deacetylating the compound, highly pure and highly efficient 3- Produce oxocarboxylic acid ester. |