abstract |
(57) [Summary]nA combination of an ACE inhibitor, an aldosterone receptor antagonist and a diuretic, a "triple therapy" combination, has been described for the treatment of cardiovascular disorders. Of particular interest is triple therapy using captopril or enalapril co-administered with low doses of spironolactone and furosemide. This triple therapy would be particularly useful for treating or preventing the progression of congestive heart failure, while avoiding or reducing aldosterone-antagonist induced side effects such as hyperkalemia. |