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filingDate 1996-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H10513386-A
titleOfInvention Multi-stage collagen-based template or implant for use in repairing cartilage damage
abstract (57) [Summary] The present invention is a template (12) useful for regeneration of articular cartilage. This template (12) is formed by combining a porous collagen sponge (collagen matrix) (13) with a dense collagen membrane (14). The dense collagen membrane (14) allows for the transfer and exchange of body fluids, nutrients, cytokines and other factors required for cartilage regeneration. The collagen matrix (13) allows the attachment and proliferation of cells commonly found in articular cartilage, especially chondrocytes (6). The collagen matrix (13) can be combined with chondrocytes in vitro, and thus, can transport cultured cells to the defect site and keep them in a position ready for transplantation. The procedure has been described for effectively using this two-step template (12) and for securing the template to the repair site.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003516803-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9113916-B2
priorityDate 1995-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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