http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H10513048-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 1996-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1998-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H10513048-A |
titleOfInvention | Screening for modulators of biomolecules |
abstract | SUMMARY OF THE INVENTION The present invention is directed to the effect of putative modulators on phenotypic sensors in one or more conditioned growth cell types with altered biomolecules, in cells where these biomolecules are normal. By comparing the effect of the type on the sensor, a method of screening for modulators of biomolecules is provided. The altered biomolecules or biochemical pathways associated with the biomolecules can produce different effects and / or phenotypic effects that can be essentially reproduced in normal cells by the effects of modulators. Also, methods of screening for modulators and characterization of modulators by comparing the effect of a modulator on multiple cells with different altered biomolecules and / or on multiple different phenotypic sensors A method is provided for assessing. The method may also be applied to characterize novel modulators with reference to known modulators, for example to identify the mechanism of action or to characterize modulator molecular interactions. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017225445-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4798921-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017512501-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020022463-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015226544-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003527110-A |
priorityDate | 1995-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.