http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H10512881-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-60 |
| filingDate | 1996-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H10512881-A |
| titleOfInvention | Novel highly potent agonists of growth hormone releasing hormone |
| abstract | (57) [Summary] Synthetic peptide having the following sequence: Q 1 -CO-Ala 2 -Asp 3 -Ala 4 -Ile 5 -Phe 6 -Thr 7 -R 8 -Ser 9 -Tyr 10 -Arg 11 -R 12 -Val 13 -Leu 14 -R 15 -Gln 16 -Leu 17 -Ser 18 -Ala 19 -Arg 20 -R 21 -Leu 22 -Leu 23 -Gln 24 -Asp 25 -Ile 26 -R 27 -R 28 -NH -Q 2 wherein Q 1 is an ω or α-ω substituted alkyl having structure (I): (Provided that [φ] is phenyl; Y is H, —NH 2 , CH 3 CONH— or CH 3 NH—; Z is H or CH 3 ; m is 1 or 2; n is 0, 1 or 2; R 2 is Ala, Abu or Aib; R 8 is Asn, Ser, Gln or Thr; R 12 is Lys or Orn; R 15 is Gly, Ala or Abu R 21 is Lys or Orn; R 27 is Met or Nle; R 28 is Ser or Asp; and Q 2 is a lower ω-co-anisino alkyl group having the formula:-(CH 2) p -NH 2 -C (NH ) = NH ( Here, p is 2-6)), and pharmaceutically acceptable addition salts with pharmaceutically acceptable organic or inorganic bases or acids. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015503512-A |
| priorityDate | 1995-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.