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publicationDate 1998-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H10511558-A
titleOfInvention Neural drug screening
abstract (57) [Summary]nCompositions for identifying lead compounds for agents useful in the diagnosis or treatment of neurological diseases or injuries include isolated netrin and those lacking in colorectal cancer (DCC) and neogenin. Such isolated natural netrin receptors. The method comprises the steps of incubating a mixture of isolated mammalian netrin, isolated native mammalian netrin receptor and a candidate agent, and determining whether the presence of the agent modulates the binding of netrin to the receptor. Contains.
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