| abstract |
(57) [Summary]nThe invention is useful for treating acne vulgaris in combination with a retinoid, such as tretinoin or isotretinoin, and at least one agent selected from antimicrobial, keratolytic and / or anti-inflammatory agents. Combination formulas using selective inhibitors of 5α-reductases 1 and / or 2, including substituted 4-aza-5α-cholestan-3-ones and related 4-aza-5α-androstan-3-one compounds Provide a way. |