http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H10505905-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-974 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 1995-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H10505905-A |
| titleOfInvention | Diagnostic test for proliferative aging of immune cells |
| abstract | (57) [Summary]nA method for distinguishing immune senescent cells from immune non-senescent cells in a cell population comprising the following steps: (1) providing a cell population; (2) subjecting the cell population to a monoclonal antibody specific for the CD28 antigen. And the antibody is labeled with a detectable label, such that the monoclonal antibody binds to cells that are positive for the antigen, and the cells that bind to the antibody are immunologically non-senescent and bind to the antibody. Cells that cannot bind are immunologically senescent; and (3) detecting cells that react with the monoclonal antibody by observing a detectable label bound to the cells, thereby rendering the immune senescent cells immune non-senescent. (A) the number of immune senescent cells in the population; (b) the number of non-senescent cells in the population; and What is the ratio of immune senescent cells to senescent cells? Measure it. Typically, the label is a fluorescent label. Typically, the cells are T cells, and a subpopulation of cells that are CD3 positive may be considered. The method of the present invention can also be used to separate and isolate immune senescent cells from immune non-senescent cells. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010070908-A1 |
| priorityDate | 1994-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.