abstract |
(57) [Summary]nLatent growth factors such as TGFβ in tissue culture or healing wounds can be activated by matrix vesicle extracts or through media of matrix vesicles stimulated by a potentiator regulator (REF). Is converted to REF includes 1,25-dihydroxyvitamin D and steroid hormones. A matrix vesicle having a REF inserted within the vesicle membrane is provided. Polymeric grafts and cell culture scaffolds having matrix vesicles, matrix vesicle extracts, REFs or latent growth factors are also provided. |