Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1995-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H10503087-A |
titleOfInvention |
Lung cancer marker |
abstract |
(57) [Summary]nThe present invention discloses isolated and purified nucleic acid sequences and corresponding amino acid sequences of novel proteins specific for human lung cancer cells. This gene is expressed at much higher levels in normal lung cells, other normal tissues and other tumor cell lines tested than in these cells. Also disclosed are three recombinant forms of the gene and protein, two of which have transmembrane regions removed and the third have amino acid changes by in vitro mutagenesis. Also disclosed are nucleic acid probes for detecting lung cancer cells from tissue biopsies and body fluids such as serum, saliva and bronchial lavage. Also disclosed is a method of expressing the antigen in a host cell and its use as an immunogen for antibody production for use in test purposes. Also disclosed are an ELISA method for measuring desquamation antigens present in patient samples and an enzyme test for measuring activity in a sample. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017206551-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004500029-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002543769-A |
priorityDate |
1994-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |