| abstract |
(57) [Summary]nThe present invention discloses various gene therapy applications using human hepatocyte iNOS cDNA clones and iNOS DNA sequences. In a preferred embodiment of the disclosed invention, gene therapy directed by iNOS is used to treat iNOS biologically for the treatment of vascular diseases and disorders, antitumor applications, and response to certain microbial infections. Specific targeting of DNA sequences encoding active proteins or protein fragments. |