| abstract |
PROBLEM TO BE SOLVED: To provide a heat shock protein synthesis inhibitor having a molecular weight of 47 kilodaltons, which can treat a disease showing a pathological condition of enhanced extracellular matrix production by suppressing collagen synthesis. . SOLUTION: A pyranopyranone compound represented by the following general formula (I) is contained as an active ingredient. Embedded image (In the formula, R 1 is a hexose residue excluding the hydroxyl group at position 1 of hexose, Ra is an amino acid residue whose α-amino group may be optionally protected, or a hydrogen atom.) |