| abstract |
(57) [Summary] [Problem] It is excellent in shape retention and percutaneous absorption, and can easily obtain a local anesthetic action by simply applying it. For example, it can remove pain at the time of injection and various pains. Gel preparation for local anesthesia, which can be easily peeled off and does not stain hands, fingers and clothes, especially a transdermal therapeutic system (TT) Provided is an external preparation for local anesthesia suitably used for transdermal or transmucosal drug administration using the principle of S) or the principle of iontophoresis. SOLUTION: An N-vinylacetamide copolymer containing N-vinylacetamide and a polymerizable monomer having a COOM group (wherein M represents a hydrogen atom, an alkali metal atom or an ammonium group) as a main component, An external preparation for local anesthesia using a gel containing a humectant, a local anesthetic, an aluminum compound and water. |