| abstract |
(57) [Summary]nPROBLEM TO BE SOLVED: To provide an inhibitor of an induction effect by TNF-α.nSOLUTION: General formula (1)nEmbedded imagen (Where R 1 Is C 1-6 R such as an alkyl group Two Is a hydrogen atom Etc., R Three Is a hydrogen atom, R Four And R 6 Is a hydrogen atom, etc. R Five Is a halogen atom, X is a hydrogen atom, A is a nitrogen atom Etc., m is 2 or 3, Y is a hydroxyl group, etc., Z is a carbon atom, etc. Show. ) Or a salt thereof as an active ingredient TNF-α-inducing effect inhibitor. |