abstract |
PROBLEM TO BE SOLVED: To provide a production method capable of synthesizing a tertiary arylamine from a primary amine in one pot with high activity and high selectivity. SOLUTION: A primary amine of the general formula 1 is reacted with two different aryl halides of the general formulas 2 and 3 in the presence of a catalyst comprising a trialkylphosphine and a palladium compound and a base. R (NH 2 ) n (1) (R is an alkyl group or a substituted or unsubstituted aryl group, n represents 1 or 2.) Ar1 (X1) m1 (2) (Ar1 is a substituted or unsubstituted aryl group , X1 is F, C l, Br or I, m1 represents an integer of 1 to 3. Ar2 (X2) m2 (3) (Ar2 is a substituted or unsubstituted aryl group different from Ar1, X2 is F, Cl, Br or I, and m2 represents an integer of 1 to 3.) |