| abstract |
A stable coating for a medical device that allows sufficient release of a drug at a specified rate in a body fluid over a desired period of time, while maintaining high pharmaceutical activity on its surface. The provision of a medical device having: The present invention provides an outer layer containing an ionic surfactant complexed to a biologically active substance, and an outer layer, wherein the biologically active substance in the storage layer can move outward from the storage layer. A medical device comprising a coating comprising a reservoir layer comprising a polymer incorporating a biologically active substance substantially free of ionic surfactants. |