abstract |
(57) [Problem] To provide a novel pyranoazine derivative having antibacterial activity, antiestrogenic activity and antitumor activity. SOLUTION: The formula (I) (Wherein, R 1 represents hydrogen, substituted or unsubstituted lower alkyl, hydroxy, lower alkoxy, carboxy, lower alkanoyl, lower alkoxycarbonyl, lower alkanoyloxy, NR 2 R 3 , nitro or halogen; W, X, One of Y and Z represents N, and the other represents the same or different and represents N or CR 4 ) or a pharmacologically acceptable salt thereof. |