abstract |
PROBLEM TO BE SOLVED: To provide a nucleic acid capable of hybridizing to a DNA molecule encoding a modulator of body weight which enables control of fat accumulation and fat content in mammals. The present invention encodes an OB polypeptide. Detectable labeled nucleic acid molecules and antisense nucleic acid molecules capable of hybridizing to DNA molecules, nucleic acids capable of hybridizing to non-coding regions of OB nucleic acids, and oligos for amplifying human genomic DNA encoding OB polypeptide A nucleotide primer is provided. |