Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16f0619af85b12c969b8ac5c7944244d |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
1997-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46ca558ac7034b44757ce2df3376c6d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2511818db549ddce6ebd49626830e9ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae636a0fe8626352aa85fbfc43b07d7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e46de41ce1199c5d2f71d4ac807a39b |
publicationDate |
1998-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H10251235-A |
titleOfInvention |
Quinazoline compound, monoclonal antibody specific to C9 base, and method for immunological measurement of pufferfish venom |
abstract |
(57) [Problem] To provide a method for collectively and easily measuring tetrodotoxin compounds, and a monoclonal antibody used for the method. SOLUTION: The method of the present invention comprises (1) a step of neutralizing a test sample after alkali hydrolysis, and (2) 2-amino- 6-hydroxymethyl-8-hydroxyquinazoline (C Measuring the amount of C9 bases in the treatment solution obtained in the step (1) by an immunological measurement method using a monoclonal antibody that specifically reacts with (9 bases); Determining the total amount of the tetrodotoxin compound from the measurements obtained. The monoclonal antibody of the present invention has the general formula (I): (Specific examples are R 1 is a hydrogen atom, R 2 is -CH It prepared using quinazoline compound represented by 2 -S-CH 2 -COOH). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7906522-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1878727-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1878727-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116120242-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116120242-B |
priorityDate |
1997-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |