| abstract |
PROBLEM TO BE SOLVED: To provide a prophylactic / therapeutic agent for Sjögren's syndrome, especially for primary Sjögren's syndrome by finding autologous antibodies and self-antigens specific for Sjögren's syndrome, especially for primary Sjögren's syndrome, Provide diagnostics. The α-fodrin or α-fodrin fragment protein of the present invention is an antigen against an autoantibody specifically found in Sjogren's syndrome, and the self-antigen is a prophylactic / therapeutic agent for an autoimmune disease, particularly, a prophylactic / therapeutic Sjogren's syndrome Agent or a diagnostic agent thereof. |