| abstract |
PROBLEM TO BE SOLVED: To provide a compound having an acyl CoA: cholesterol acyltransferase inhibitory activity. SOLUTION: For example, the formula: [In the formula, ring A represents a pyrimidine ring which may have a substituent, R 2 represents a hydrogen atom, an alkyl group, a substituted alkyl group, and the like, Z represents a bond, —NH—, and a carbon atom of 1; Or 2 represents an alkylene group or -CH = CH-, Y represents an alkyl group, a substituted alkyl group, an aromatic group or a substituted aromatic group, and L represents an alkyl group, a substituted alkyl group, an aromatic group or a substituted aromatic group. Represents a group or the like. A naphthyridine derivative or an acid addition salt thereof. |