| abstract |
PROBLEM TO BE SOLVED: To treat a viral infection as an antitumor agent and to regulate embryonic growth and tissue homeostasis. It is desirable to use ICE LAP polypeptides, especially human ICE LAP polypeptides. The present invention provides: a) extracting DNA or RNA from an individual; and b) ICE LAP-1,2, Detecting a mutation in the nucleotide sequence of 3, 4, 6 or 7 or a) extracting a tissue sample from the individual; b) measuring the polypeptide level of the ICE LAP in the sample; and c) in the individual The ICE measured Comparing the level of LAP to the level measured in the control sample to determine whether the level of ICE LAP in the individual is increasing or decreasing. Methods for diagnosing or detecting susceptibility to osteoarthritis are provided. |