| abstract |
PROBLEM TO BE SOLVED: To provide ischemic and / or non-cardiac tissue damage caused by hypoxia by administering an effective amount of glycogen phosphorylase inhibitor to a patient, especially ischemia in a diabetic patient. Providing a method for preventing injury (eg, arterial embolism). SOLUTION: The following general formula I A glycogen phosphorylase inhibitor represented by the formula: A specific example is 5-chloro-1H-indole-2-carboxylic acid [(1S)-((R) -hydroxydimethylcarbamoylmethyl) -2-phenylethyl] -amide. |