Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13c67b67baa787a0a0f4b583c574f469 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_527cbadc3d8cf81b5bf931c0dd99b3c1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
1997-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_094b377af72c895f09749a1611f416d8 |
publicationDate |
1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H10191977-A |
titleOfInvention |
Thioredoxin variants and factors that enhance the transcriptional activity of AP-1 containing the variants |
abstract |
PROBLEM TO BE SOLVED: To provide a modified thioredoxin characterized by being stable under non-reducing conditions, and an AP-1 transcription activity enhancing factor containing the thioredoxin and Ref-1. The purpose is to do. SOLUTION: The modified thioredoxin of the present invention is characterized in that the Cys residue in the active center is not modified and at least one or all other Cys residues are substituted with other amino acid residues. Furthermore, the AP-1 transcription activity enhancer of the present invention is characterized in that the thioredoxin and Ref-1 are S -S bonds. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004087917-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022196683-A1 |
priorityDate |
1997-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |