| abstract |
(57) Abstract: A compound comprising at least one N-substituted glycine monomer and comprising 2 to 10 monomers selected from N-substituted glycine or amino acids, A compound having a specific sequence having at least one monomer whose side chain is a substituent containing an arene group, and at least one monomer whose side chain is a substituent having an overall positive charge; A low-density lipoprotein-binding compound having a specific charge. [Effect] It has specifically excellent binding to low-density lipoprotein, but does not induce the production of bradykinin, activation of blood cells or adsorption to compounds, activation of blood coagulation system, etc. Because of its excellent safety, it is advantageous as a reagent for adsorbents for removing low-density lipoprotein from body fluids such as whole blood and plasma, and also as a drug and carrier of drugs for diseases involving low-density lipoprotein. Can be used. |