http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H101617-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
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filingDate 1996-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9512cbdd05931eb8d7131950e2a13741
publicationDate 1998-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H101617-A
titleOfInvention Purification method of pink chlorophyll derivative
abstract PROBLEM TO BE SOLVED: To produce a purified pink chlorophyll derivative on an industrial scale, and to remove impurities contained in a reaction solution of the pink chlorophyll derivative without using an organic solvent. To provide a method for producing high-purity pink chlorophyll derivatives at low cost. SOLUTION: A pink chlorophyll derivative reaction solution is A removal step of adsorbing unreacted substances and by-products by passing through a chromatography column filled with the first adsorbent, and an adsorption step of adsorbing a pink chlorophyll derivative on the chromatography column filled with the second adsorbent Washing the chromatographic column with water to remove coexisting sulfites, sulfates, and the like, and washing the pink chlorophyll derivative remaining in the chromatographic column filled with the second adsorbent with sodium chloride, Using an organic solvent to remove impurities contained in the reaction solution of the pink chlorophyll derivative, comprising an elution step of eluting a 0.1 M / l to 2.0 M / l aqueous solution of potassium chloride or a mixture thereof as an eluent. For producing a pink chlorophyll derivative that can be removed without any problems
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4727190-A
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type http://data.epo.org/linked-data/def/patent/Publication

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