abstract |
(57) Abstract: A polynucleotide or the like is chemically modified or labeled so as to be easily detected. SOLUTION: The general formula: Or [Formula 2] (Wherein P is a phosphate residue, S is a sugar or monosaccharide residue, B is a base residue, and when the nucleotide is a deoxyribonucleotide, a phosphate residue The group is 3 'and / or 5' of the sugar residue At the 2 ', 3' and / or 5 'positions if the nucleotide is a ribonucleotide, the base is a purine or pyrimidine, and the base is a pyrimidine or purine, respectively. Has the above-mentioned base bound from the N1 or N9 position to the 1 ′ position of the sugar residue, The Sig is a chemical residue covalently bonded to the sugar or monosaccharide residue S or the phosphate residue P of the nucleotide, and serves as a signal itself or detects itself or It can signal its existence. ) |