abstract |
(57) [Problem] To provide an excellent PGI 2 receptor agonist. SOLUTION: The formula: [Wherein, R 1 is H or a substituent, m is 1-3, Ar is an aromatic group which may have a substituent, X is a bond or the number of atoms which may have a substituent 1 6 straight-chain divalent group, Y is -S -, - O-or -N (R 2) - (R 2 represents H or a substituent), Z is -N = or -C (R 3 ) = (R 3 represents H or a hydrocarbon group), the A ring represents a benzene ring, and the B ring represents a 5- to 7-membered ring which may have a substituent. Its salt. |