http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H10139768-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c8d4dc7bd1a30d8fda907fceaeb4e69 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 |
| filingDate | 1996-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e684e99017e4ffc421e040be4a06f290 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc9d274d1a1fc2c0ca2454d323871d28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b7d9b9b0647179e4a0dc11996fcc8cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_409e3adce7002bc8fbfdea9f5edf12aa |
| publicationDate | 1998-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H10139768-A |
| titleOfInvention | Method for producing naphthalene derivative |
| abstract | (57) [Problem] To provide a novel method for producing a naphthalene derivative. SOLUTION: 6-hydroxy-2-naphthaldehyde is reacted with 2,4-thiazolidinedione to form 5- (6 -Hydroxy-2-naphthyl) methylene-2,4-thiazolidinedione followed by 5- (6-hydroxy-2) -Naphthyl) methyl-2,4-thiazolidinedione. Further, this is reacted with a benzyl derivative to produce 5- (6-substituted benzyloxy-2-naphthyl) methyl-2,4-thiazolidinedione represented by the following formula. Embedded image Y: protecting group such as halogen atom R 1 to R 5 : hydrogen atom, halogen atom, alkyl group etc. A: C 1 to C 3 alkylene group etc. Effect The method of the present invention has a blood glucose and blood lipid lowering action. In addition, it is useful as an industrial method for producing a naphthylmethylthiazolidinedione derivative useful as a preventive / therapeutic agent for diabetes and hyperlipidemia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6541493-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003040877-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7015345-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0136401-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0073252-A1 |
| priorityDate | 1996-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.