| abstract |
(57) [Summary] [Problem] To provide a skin external preparation for improving a tsukusu, such as a cosmetic or a medicine, which can improve the action of a tsukusu. Kind Code: A1 Abstract: A skin for ameliorating tsukusui containing one or more compounds (emodin, aloe-emodin, etc.) selected from the group consisting of a compound represented by the following general formula (I) and a physiologically acceptable salt thereof as an active ingredient. Obtain an external preparation. Embedded image [In formula (I), R 1 represents a hydroxyl group, a low-chain-length acyloxy group or a sugar residue, R 2 represents a hydrogen atom, a hydroxyl group, an acyloxy group, a hydroxymethyl group or a carboxyl group; R 3 represents a methyl group, a carboxyl group or a hydrogen atom, A represents a group represented by a carbonyl group or a CH-R 4, R 4 represents a sugar residue or an optionally substituted anthranyl group, and R 5 represents a hydrogen atom or an acyl group. ] |