| abstract |
(57) [Problem] To provide a nitric oxide synthase inhibitor. SOLUTION: The general formula: Wherein X is N or CH, R 1 is a lower alkyl group, R 2 represents a group such as a group —NHR 3 (R 3 is a lower alkoxy group or a phenyl lower alkyl group having 1 to 3 halogen atoms on a phenyl ring). ] A nitric oxide synthase inhibitor comprising, as an active ingredient, a condensed pyrimidine derivative represented by the following formula: |