| abstract |
PROBLEM TO BE SOLVED: To provide a novel imino derivative as an inhibitor of bone resorption and a vitronectin receptor antagonist. SOLUTION: The imino derivative has a formula I R 1 -YABD-E-FG (I) wherein R 1 , Y, A, B, D, E, F and G are (Having the meaning shown in the claims). Methods of making these compounds and the use of these compounds as medicaments are also disclosed. The compounds according to the invention are used as hydronectin receptor antagonists and as inhibitors of bone resorption. |