| abstract |
(57) [Summary] (1) The following general formula (1): [Wherein, R 1 and R 3 represent a phenyl group which may have a substituent, R 2 represents a phenyl group or a cycloalkyl group which may have a substituent, and a wavy line indicates the bonding state. Represents that either E or Z may be used. Where R 1 , When R 2 and R 3 are an unsubstituted phenyl group, R 1 and R 3 Excluding the case where 2 is an unsubstituted phenyl group and R 3 is a 4-ethoxyphenyl group], or a salt thereof, and a medicament containing the same as an active ingredient. [Effect] Since it selectively and strongly inhibits ACAT in macrophages, it is useful as an agent for preventing and treating arteriosclerosis. |