| abstract |
(57) [Summary] [Solution] The following formula (I): [the symbols in the formula are (1) R 1 = H, R 2 = H, t-butyldiphenylsilyl (TBDPS), etc., R 3 = Ac; (2) R 1 = Me, R 2 = TBDPS, R 3 = Ac; or (3) R 1 = TMS, R 2 = TBDP S, R 3 = H, Ac, or -P (O) (OH) H]], or a vinylated deoxyguanosine derivative or a salt thereof. Embedded image [Effect] Since it is chemically stable and can react with a nucleophilic molecule such as cytidine to form a covalent bond, it is useful as an intermediate for producing an antisense oligonucleic acid having crosslinkability. |